Associate Professor Department of Immunology Centre for Innovative Research in Natural and Medical Sciences Medical Faculty University of Rzeszow, Associate Professor Faculty of Biotechnology S.Gzhytskyi National University of Veterinarian Medicine and Biotechnologies викладає курс "ІТ в сучасній біології"
Olexandr Korchynskyi is Senior Scientist at the Department of Molecular Immunology, Institute of Biochemistry, Natl.Acad.Sci. of Ukraine, Kyiv, Ukraine (2020 - to date). Since 2016 Dr.Korchynskyi serves in a parallel as an Associate Professor at the Department of Immunology, Medical Faculty, and the Centre for Innovative Research in Medical and Natural Sciences and Institute for Experimental Medicine, Rzeszów University (Poland).
O.Korchynskyi received his PhD in Biochemistry in 1993. He received an extensive training at the field of cell signaling, cell and molecular biology and immunology from several famous European institutions: Ludwig Institute for Cancer Research, Uppsala, Sweden, Netherlands Cancer Institute, Amsterdam and Leiden Universities, The Netherlands. During 2002-2007 Dr.Korchynskyi was trained at the University of North Carolina at Chapel Hill, NC; University of California at San Diego, CA and Virginia Commonwealth University, Richmond, VA, U.S.A. Olexandr Korchynskyi authored and co-authored over 40 scientific papers, including works published in Nature and Science that scored over 3000 citations. Dr.Korchynskyi’s top-cited scientific publication (JBC’2002) was devoted to understanding and description of Bone Morphogenetic Proteins (BMP)/Smad response element in a direct BMP target gene Id1. Based on such understanding a highly specific and sensitive synthetic reporter system specific to BMP/Smad signals was created. This reporter system was validated in vivo in BMP reporter mice (Monteiro et al., 2004) and currently is the best such system available for scientific community. This work was cited in up to 30 top-level scientific publications published by other people over the world.
Dr.Korchynskyi received as a project Leader an OPUS12 Grant award from NCN (Poland) in 2017 (1,067,000 PLN) and in 2021 Natl. Sci.Fund of Ukraine award (6,150,000 UAH).
Under funding support from his OPUS12 NCN Grant Dr.Korchynskyi organized a biosafety level II lab (BSL-II) at Rzeszów University. He in a person created over one hundred different adenoviral constructs. In a part he developed two versions of AdvC5-based vectored vaccines against SARS2/COVID-19 vaccines that were validated into experimental animals and will be applied for patenting.
Under the funding support of Ukrainian Ministry of Education Grant Korchynskyi/Chernyshenko’s team recently developed a bacterial and mammalian expression systems for recombinant snake proteins to be used as the hemostatic ccompounds. Currently these products are at the stage of production technology optimization